HCID 69687692, compound → HCID 69688207, compound

HRID 1265610Notes

Reaction equation

HRID 1265610 reaction equation
CO[C:3](=[O:15])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[N:11]=[CH:12][O:13][CH:14]=2)[CH:5]=1.[C:16]([O:19][C:20]([CH3:23])([CH3:22])[CH3:21])(=[O:18])[CH3:17].[Li]>>[C:20]([O:19][C:16](=[O:18])[CH2:17][C:3]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[N:11]=[CH:12][O:13][CH:14]=2)[CH:5]=1)=[O:15])([CH3:23])([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 69687692HCID 69687692, compoundHCID 86586795Lithium Tert-butyl Acetate

Product 1

HCID 69688207HCID 69688207, compound

Procedure

3-Oxazol-4-yl-benzoic acid methyl ester (0.85 g) was treated with lithium tert.-butyl acetate according to the general procedure K (method b) to give crude 3-(3-oxazol-4-yl-phenyl)-3-oxo-propionic acid tert-butyl ester (1.46 g) as a pale-yellow oil.

Sources & evidence

ORD record
ord-fc45393ec8324281a6dd2490d5fb4209
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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