HCID 69687940, compound → HCID 69687476, compound

HRID 1265637Notes

Reaction equation

HRID 1265637 reaction equation
CO[C:3](=[O:18])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[NH:11][C:12]([CH:15]([CH3:17])[CH3:16])=[N:13][CH:14]=2)[CH:5]=1.[C:19]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])(=[O:21])[CH3:20].[Li]>>[C:23]([O:22][C:19](=[O:21])[CH2:20][C:3]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]2[NH:11][C:12]([CH:15]([CH3:16])[CH3:17])=[N:13][CH:14]=2)[CH:5]=1)=[O:18])([CH3:26])([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 69687940HCID 69687940, compoundHCID 86586795Lithium Tert-butyl Acetate

Product 1

HCID 69687476HCID 69687476, compound

Procedure

3-(2-Isopropyl-3H-imidazol-4-yl)-benzoic acid methyl ester was treated with lithium tert.-butyl acetate according to the general procedure K (method b) to give crude 3-[3-(2-isopropyl-3H-imidazol-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (0.25 g) as a pale-yellow oil.

Sources & evidence

ORD record
ord-bfe1ac12af4f4d8a8da072443c122a54
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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