HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-[3-(3-Methoxymethyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester → (4-Chloro-5-dimethylamino-2-{3-[3-(3-methoxymethyl-isoxazol-5-yl)-phenyl]-3-oxo-propionylamino}-phenyl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-[3-(3-Methoxymethyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester | HCID 69687567 | — |
| Reactant | (2-Amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester | HCID 69688689 | — |
| Product | (4-Chloro-5-dimethylamino-2-{3-[3-(3-methoxymethyl-isoxazol-5-yl)-phenyl]-3-oxo-propionylamino}-phenyl)-carbamic acid tert.-butyl ester | HCID 86586817 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester (Example J1) and 3-[3-(3-methoxymethyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester (Example K9) according to the general procedure M. Obtained as a yellow solid (205 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-e59430b9996d4b2ead413d4cc74e38a5 |
| Source note | uspto-grants-2003_04 |