HuagongsheHuagongshe Chemistry Print Report · For research reference only
(RS)-3-{3-[3-methyl-4-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-5-yl]-phenyl}-3-oxo-propionic acid tert.-butyl ester → HCID 86586827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (RS)-3-{3-[3-methyl-4-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-5-yl]-phenyl}-3-oxo-propionic acid tert.-butyl ester | HCID 69688176 | — |
| Reactant | (2-Amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester | HCID 69688689 | — |
| Product | HCID 86586827 | HCID 86586827 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-chloro-5-dimethylamino-phenyl)-carbamic acid tert.-butyl ester (Example J1) and (RS)-3-{3-[3-methyl-4-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-5-yl]-phenyl}-3-oxo-propionic acid tert.-butyl ester (Example K13) according to the general procedure M. Obtained as a light yellow solid (187 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-a491c3447f614ee48a4efc8a1bbca4fd |
| Source note | uspto-grants-2003_04 |