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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265702Generated: October 30, 2026

3-(2-Cyano-pyridin-4-yl)-3-oxo-propionic acid tert-butyl ester → HCID 86586863, compound

https://huagongshe.com/reaction/1265702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Cyano-pyridin-4-yl)-3-oxo-propionic acid tert-butyl esterHCID 69592816—
ReactantCarbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 76849205—
ProductHCID 86586863HCID 86586863—

Reaction Steps

The title compound was prepared from [2-amino-5-(2,2,2-trifluoro-ethoxy)-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example J21) and 3-(2-cyano-pyridin-4-yl)-3-oxo-propionic acid tert.-butyl ester (Example K3) according to the general procedure M. Obtained as a light brown solid (262 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-12c60c2d790346c5a52f9149dbe78017
Source noteuspto-grants-2003_04