HuagongsheHuagongshe Chemistry Print Report · For research reference only
(RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester → HCID 86586867, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester | HCID 12048028 | — |
| Reactant | (2-Amino-4-cyano-5-dimethylamino-phenyl)-carbamic acid tert-butyl ester | HCID 69687295 | — |
| Product | HCID 86586867 | HCID 86586867 | — |
Reaction Steps
The title compound was prepared from (2-amino-4-cyano-5-dimethylamino-phenyl)-carbamic acid tert-butyl ester (Example J23) (276 mg, 1.0 mmol) and (RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester (Example K5) (402 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown foam (360 mg, 59%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-6d4901b65a4a4c7da86708b8a0d69813 |
| Source note | uspto-grants-2003_04 |