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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265712Generated: October 31, 2026

3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl ester → HCID 86586874, compound

https://huagongshe.com/reaction/1265712

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl esterHCID 69592871—
ReactantHCID 69688187HCID 69688187—
ProductHCID 86586874HCID 86586874—

Reaction Steps

The title compound was prepared from (2-amino-4-cyano-5-pyrrolidin-1-yl-phenyl)-carbamic acid tert-butyl ester (Example J28) (302 mg, 1.0 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K4) (301 mg, 1.0 mmol) according to the general procedure M. Obtained as a light brown foam (420 mg, 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-447977b3b9d94426a6c7c4acc068b4a2
Source noteuspto-grants-2003_04