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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265722Generated: October 30, 2026

Carbamic acid,[2-amino-5-(methylpropylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 86586886, compound

https://huagongshe.com/reaction/1265722

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,[2-amino-5-(methylpropylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486655—
Reactant3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl esterHCID 69592871—
ProductHCID 86586886HCID 86586886—

Reaction Steps

The title compound was prepared from [2-amino-5-(methyl-propyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J35) (360 mg, 1.04 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K4) (312 mg, 1.04 mmol) according to the general procedure M. Obtained as a light red foam (270 mg, 45%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-444f1fdb34bb4468b4ad6c5fcb6a2ba1
Source noteuspto-grants-2003_04