Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265726Generated: October 31, 2026

Carbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → HCID 86586890, compound

https://huagongshe.com/reaction/1265726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486615—
Reactant3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl esterHCID 69592871—
ProductHCID 86586890HCID 86586890—

Reaction Steps

The title compound was prepared from [2-amino-5-(isopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example J37) (350 mg, 1.01 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K4) (304 mg, 1.01 mmol) according to the general procedure M. Obtained as a light brown foam (380 mg, 66%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-bbdb8559e29a4b4a96be1446f14e15d8
Source noteuspto-grants-2003_04