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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265775Generated: October 31, 2026

Trifluoroacetic acid → HCID 18613113, compound

https://huagongshe.com/reaction/1265775

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586823HCID 86586823—
SolventDichloromethaneHCID 6344—
ProductHCID 18613113HCID 18613113—

Reaction Steps

The title compound was prepared from (RS)-[4-chloro-5-(methyl-propyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert-butyl ester (Example M27) (0.4 g, 0.64 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a pale yellow solid (110 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-aa63eda79fdb47fda9428f3cdb09df59
Source noteuspto-grants-2003_04