HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 69688895, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86586828 | HCID 86586828 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69688895 | HCID 69688895 | — |
Reaction Steps
The title compound was prepared from (RS)-[4-chloro-5-(cyclopropyl-methyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert.-butyl ester (Example M33) (200 mg, 0.313 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (54 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-6d5d47ec09ea4b2e96f8e95f00eae023 |
| Source note | uspto-grants-2003_04 |