HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18613447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86586841 | HCID 86586841 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18613447 | HCID 18613447 | — |
Reaction Steps
The title compound was prepared from (RS)-[4-fluoro-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-5-pyrrolidin-1-yl-phenyl]-carbamic acid tert.-butyl ester (Example M49) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as an orange solid (72 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-09970d94542b42dd861032c359e89c42 |
| Source note | uspto-grants-2003_04 |