HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18613135, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86586914 | HCID 86586914 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18613135 | HCID 18613135 | — |
Reaction Steps
The title compound was prepared from (RS)-{5-dimethylamino-2-[3-oxo-3-(3-{2-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-2H-pyrazol-3-yl}-phenyl)-propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert.-butyl ester (Example M69) (237 mg, 0.36 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as an off-white solid (48 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-42567f2ecc15404cae8c7db23ca970a3 |
| Source note | uspto-grants-2003_04 |