HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 18613509, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86586915 | HCID 86586915 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 18613509 | HCID 18613509 | — |
Reaction Steps
The title compound was prepared from (RS)-{5-dimethylamino-2-[3-oxo-3-(3-{5-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-[1,2,3]triazol-1-yl}-phenyl) -propionylamino]-4-trifluoromethyl-phenyl}-carbamic acid tert.-butyl ester (Example M72) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a light yellow solid (179 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-723310a5799948b29da31e0e0667c9d9 |
| Source note | uspto-grants-2003_04 |