Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265836Generated: October 31, 2026

Trifluoroacetic acid → HCID 18613425, compound

https://huagongshe.com/reaction/1265836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586865HCID 86586865—
SolventDichloromethaneHCID 6344—
ProductHCID 18613425HCID 18613425—

Reaction Steps

The title compound was prepared from (RS)-[4-methyl-5-(methyl-propyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionylamino)-phenyl]-carbamic acid tert-butyl ester (Example M80) (0.42 g, 0.71 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as a pale yellow solid (200 mg, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-496c0d3c16854d9aa6832d2c7947d524
Source noteuspto-grants-2003_04