Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265852Generated: October 31, 2026

Trifluoroacetic acid → HCID 18613433, compound

https://huagongshe.com/reaction/1265852

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86586885HCID 86586885—
SolventDichloromethaneHCID 6344—
ProductHCID 18613433HCID 18613433—

Reaction Steps

The title compound was prepared from (RS)-[5-(methyl-propyl-amino)-2-(3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example M102) (0.15 g, 0.22 mmol) by treatment with TFA in CH2Cl2 according to the general procedure N. Obtained as an off-white solid (31 mg, 30%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-0766e2a8ba1b49c380519df72ee580c1
Source noteuspto-grants-2003_04