Chloride → HCID 18613522, compound

Participants

Reaction Steps

The title compound was prepared from 2-[3-(5-hydroxymethyl-[1,2,3]triazol-1-yl)-phenyl]8-(isobutyl-methyl-amino)-4-oxo-4,5-dihydro-3H -benzo[b][1,4]diazepine-7-carbonitrile (Example 111) (200 mg, 0.45 mmol) by reaction with thionylchloride in dichloromethane and subsequent treatment of the corresponding chloride with pyrrolidine in DMF according to the method described in Example 45. Obtained as a light yellow solid (140 mg, 63%).

Provenance & Evidence