1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine → HCID 12116356, compound

Participants

Reaction Steps

The procedure of Example 1 is repeated using 3.9 g (25 mmol) of 1-oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine, 6.18 g (60 mmol) of tert-butyl nitrite, 15 mg (0.025 mmol) of (S,S)-(+)-N,N-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II) mmol) in 100 mL of pyridine and 11.25 g (50 mmol) of 2-(2-phenylallyloxy)-aniline in 20 mL of pyridine. The crude product obtained is purified by liquid chromatography (2.5% ethyl acetate/heptane) to give 2.5 g of an off-white oil in 27.4% yield. MS [M+1] 366

Provenance & Evidence