Phenylboronic Acid → HCID 70009406, compound

Participants

Reaction Steps

Using a procedure as described in Example 50(b), the title compound was synthesized from 6-iodo-7-methyl-3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-one (Example 50(a)), and phenylboronic acid to give a white solid in 70% yield: 1H NMR (DMSO-d6) δ 2.23 (s, 3H), 3.46 (bs, 2H), 4.13 (bs, 2H), 7.17 (t, 1H, J=7.5 Hz), 7.45-7.56 (m, 5H), 7.76 (d, 1H, J=7.5 Hz), 7.84 (d, 1H, J=7.5 Hz), 8.29-8.31 (m, 1H). LRMS (M+) 276. Anal. (C18H16N2).0.4 H2O) C, H, N.

Provenance & Evidence