3-Pyrroline → HCID 70009963, compound

HRID 1266045Notes

Reaction equation

Cl[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:18]3[CH2:19][CH2:20][C:21]4[NH:22][C:23](=[O:26])[CH:24]=[CH:25][C:16]([C:17]=43)=[CH:15][N:14]=2)=[CH:9][CH:8]=1)[CH2:3][CH:4]([CH3:6])[CH3:5].[NH:27]1[CH2:31][CH:30]=[CH:29][CH2:28]1>>[N:27]1([CH:2]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[N:18]4[CH2:19][CH2:20][C:21]5[NH:22][C:23](=[O:26])[CH:24]=[CH:25][C:16]([C:17]=54)=[CH:15][N:14]=3)=[CH:9][CH:8]=2)[CH2:3][CH:4]([CH3:6])[CH3:5])[CH2:31][CH:30]=[CH:29][CH2:28]1

Participants

Reactant 2

HCID 660593-Pyrroline

HCID 69701695HCID 69701695, compound

Product 1

HCID 70009963HCID 70009963, compound

Conditions

Temperature: 60 °C

Procedure

This compound was prepared from intermediate 229a and 6 equivalents of 3-pyrroline according to the procedure described in Example 171, with the exception of heating to 60° C. Received 83.3 mg (30%)

Sources & evidence

ORD record: ord-e896792985bc44e7a465f5af0349ea6b
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06548494B1

Reaction notes

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