HCID 69702327, compound → HCID 70008109, compound

HRID 1266046Notes

Reaction equation

HRID 1266046 reaction equation
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:14]3[CH2:15][C@H:16]([CH3:23])[C:17]4[NH:18][C:19](=[O:22])[CH:20]=[CH:21][C:12]([C:13]=43)=[CH:11][N:10]=2)=[CH:5][CH:4]=1>C(#N)C>[CH3:23][C@@H:16]1[C:17]2[NH:18][C:19](=[O:22])[CH:20]=[CH:21][C:12]3=[CH:11][N:10]=[C:9]([C:6]4[CH:7]=[CH:8][C:3]([CH2:2][N:14]5[CH2:15][CH2:16][CH2:17][CH2:13]5)=[CH:4][CH:5]=4)[N:14]([C:13]=23)[CH2:15]1

Participants

3

Reactant 1

HCID 69702327HCID 69702327, compound

Product 1

HCID 70008109HCID 70008109, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

This compound was prepared from intermediate 221b and the appropriate amine using the procedure described in Example 171, with the exception of using acetonitrile as solvent. Received 50 mg (11%).

Sources & evidence

ORD record
ord-77df01bb727e4e748ac85c946e9bf514
Source dataset
uspto-grants-2003_04
Patent number
US06548494B1

Reaction notes

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