反应详情

A solution of 2,6,7-trichloro-3-pyridin-2-yl-quinoxaline (0.50 g) and 3-methoxy-propylamine (0.28 g) in toluene (20 mL) was refluxed under nitrogen for 16 hours. After refluxing, the reaction mixture was cooled, filtered, and concentrated under vacuum. The residue was recrystallized from methanol and water to give the product as a yellow solid (0.45 g); mp 99.5-100.5° C.

1. temperatureAfter refluxing
2. temperaturethe reaction mixture was cooled
3. filtrationfiltered
4. concentrationconcentrated under vacuum
5. customThe residue was recrystallized from methanol and water