Hexylamine → HCID 9905637, compound

HRID 1266239Notes

Reaction equation

CO[C:3](=[O:19])[CH:4]([C:11]1[CH:16]=[CH:15][C:14]([F:17])=[C:13]([F:18])[CH:12]=1)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=1.[CH2:20]([NH2:26])[CH2:21][CH2:22][CH2:23][CH2:24][CH3:25]>>[F:18][C:13]1[CH:12]=[C:11]([CH:4]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][N:6]=2)[C:3]([NH:26][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[O:19])[CH:16]=[CH:15][C:14]=1[F:17]

Participants

Reactant 2

HCID 8102Hexylamine

HCID 69779253HCID 69779253, compound

Product 1

HCID 9905637HCID 9905637, compound

Procedure

The title compound, amorphous, MS: m/e=333.3 (M+H+) was prepared in accordance with the general method of example 22(a) from (RS)-2-(3,4-difluoro-phenyl)-2-pyridin-2-yl-acetic acid methyl ester and hexylamine.

Sources & evidence

ORD record: ord-1bf8402f6b834f2589554d7faad373f1
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06548522B1

Reaction notes

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