HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluorotoluene → (5-Chloro-2-fluoro-4-methylphenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluorotoluene | HCID 118475 | — |
| Reactant | (2,5-Difluoro-4-methylphenyl)methanol | HCID 18550538 | — |
| Product | (5-Chloro-2-fluoro-4-methylphenyl)methanol | HCID 18550823 | — |
Reaction Steps
(5-Chloro-2-fluoro-4-methyl-phenyl)-methanol was prepared in analogous fashion to (2,5-difluoro-4-methyl-phenyl)-methanol using 2-chloro-5-fluorotoluene as starting material. 1H NMR (400 MHz, CDCl3) δ 7.38 (d, 1H, J=6.8 Hz), 6.92 (d, 1H, J=10 Hz), 4.69 (s, 2H), 2.34 (s, 3H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548526B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-d0215fca786243ef9e3f5890e888cd04 |
| Source note | uspto-grants-2003_04 |