HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tri-o-tolylphosphine → HCID 17935614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tri-o-tolylphosphine | HCID 80271 | — |
| Reactant | HCID 17935607 | HCID 17935607 | — |
| Reactant | Tri(butyl)vinyltin | HCID 53438229 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 17935614 | HCID 17935614 | — |
| Product | HCID 18551161 | HCID 18551161 | — |
Reaction Steps
By heating 4-(4-bromophenyl)-2-hydroxy-4-methyl-2-trifluoromethyl-valeric acid ethyl ester, tributylvinyltin, tri-o-tolylphosphine and bis-tri-o-tolylphosphine-palladium(II) chloride in dimethylformamide to 120° C., 2-hydroxy-4-methyl-2-trifluoromethyl-4-(4-vinylphenyl)-valeric acid ethyl ester, which provides the title compound, melting point 73-74° C., by alkaline saponification, is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548534B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-58c0e715b845404d8cbed17ab1be2bfc |
| Source note | uspto-grants-2003_04 |