2-Nitrophenol → HCID 7434133, compound

Participants

Reaction Steps

To a solution of 2-nitrophenol (1.27 g, 9.13 mmol) in acetone (100 mL) was added solid potassium carbonate (1.27 g, 9.13 mmol) followed by 6-chloro-8-(chloromethyl)benzo-1,3-dioxan (1.0 g, 4.57 mmol) and the solution was refluxed for 16 hours. Solvent was evaporated and the residue was purified by column chromatography to give 1-[(6-chloro(2H,4H-benzo[e]1,3-dioxin-8-yl))methoxy]-2-nitrobenzene, a compound of formula (3).

Provenance & Evidence