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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266508Generated: November 2, 2026

Trifluoroacetic acid → HCID 22708233, compound

https://huagongshe.com/reaction/1266508

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 22708251HCID 22708251—
SolventDichloromethaneHCID 6344—
ProductHCID 22708233HCID 2270823375.8%

Reaction Steps

Similarly to the procedure of Example 1-9, 170 mg (0.374 mmol) of tert-butyl 2-(4-{[(1-{[(2,4-dimethylphenyl)amino]carbonyl}propyl)amino]methyl}phenoxy)-2-methylpropionate (Example 1-7) are reacted with 0.72 ml (9.35 mmol) of trifluoroacetic acid in 3 ml of dichloromethane to give 113 mg (72%) of 2-(4-{[(1-{[(2,4-dimethylphenyl)amino]carbonyl}propyl)amino]methyl}phenoxy)-2-methyl-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548538B2
Source datasetuspto-grants-2003_04
ORD IDord-306acb7bd0374ef8b8fe52f0027db8df
Source noteuspto-grants-2003_04