2-(Phenoxazin-10-yl)ethyl methanesulfonate → Ethyl 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-hexyloxypropanoate

HRID 1266545Notes

Reaction equation

HRID 1266545 reaction equation
CS([O:5][CH2:6][CH2:7][N:8]1[C:21]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[O:15][C:14]2[C:9]1=[CH:10][CH:11]=[CH:12][CH:13]=2)(=O)=O.O[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][CH:30]([O:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:25][CH:24]=1>>[CH:20]1[C:21]2[N:8]([CH2:7][CH2:6][O:5][C:23]3[CH:24]=[CH:25][C:26]([CH2:29][CH:30]([O:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[C:31]([O:33][CH2:34][CH3:35])=[O:32])=[CH:27][CH:28]=3)[C:9]3[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=3)[O:15][C:16]=2[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 112204632-(Phenoxazin-10-yl)ethyl methanesulfonateHCID 21930968Ethyl 3-(4-hydroxyphenyl)-2-hexyloxypropanoate

Product 1

HCID 9914041Ethyl 3-[4-[2-(phenoxazin-10-yl)ethoxy]phenyl]-2-hexyloxypropanoateYield 53%

Procedure

The title compound (0.52 g, 53%) was prepared as a pale yellow oil from 2-(phenoxazin-10-yl)ethyl methanesulfonate (0.6 g and 1.97 mmol) and ethyl 3-(4-hydroxyphenyl)-2-hexyloxypropanoate (0.70 g, 2.4 mmol) obtained in preparation 8 by an analogous procedure to that described in example 6 (Method B).

Workup

  1. customobtained in preparation 8 by an analogous procedure to

Sources & evidence

ORD record
ord-c7d5b4f2a244465d83f7391442febda4
Source dataset
uspto-grants-2003_04
Patent number
US06548666B1

Reaction notes

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