HCID 10140557, compound → HCID 20577803, compound

HRID 1266587Notes

Reaction equation

HRID 1266587 reaction equation
[CH2:1]([S:6][C:7]1[S:8][C:9]2[CH:15]=[C:14]([S:16]([N:19]([CH2:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C@H:20]([CH3:24])[C:21](O)=[O:22])(=[O:18])=[O:17])[CH:13]=[CH:12][C:10]=2[N:11]=1)[CH2:2][CH2:3][CH2:4][CH3:5].C(Cl)(=O)C(Cl)=O.Cl.[OH:39][NH2:40].C([O-])(O)=O.[Na+].C1COCC1.O>>[OH:39][NH:40][C:21](=[O:22])[C@H:20]([N:19]([S:16]([C:14]1[CH:13]=[CH:12][C:10]2[N:11]=[C:7]([S:6][CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[S:8][C:9]=2[CH:15]=1)(=[O:18])=[O:17])[CH2:25][C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1)[CH3:24]

Participants

3

Reactant 2

HCID 10140557HCID 10140557, compoundHCID 131723855HCID 131723855, compound

Product 1

HCID 20577803HCID 20577803, compound

Procedure

Using various N-benzylsulfonyl acid derivatives as a starting material obtained in Example 33, the following titled compounds were prepared by applying the above method under the condition of oxalylchloride/hydroxyamine hydrochloride/NaHCO3/THF/H2O.

Sources & evidence

ORD record
ord-012b6d966a1c4bed8c52acef67df2462
Source dataset
uspto-grants-2003_04
Patent number
US06548667B2

Reaction notes

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