HCID 131723856, compound → HCID 18551632, compound

HRID 1266588Notes

Reaction equation

C([C:3](CC)([C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1)[CH:4]([P:25](=[O:28])([O-:27])[O-:26])[NH:5][S:6]([C:9]1[CH:24]=[CH:23][C:12]2[N:13]=[C:14]([S:16][CH2:17][CH2:18][CH2:19][CH2:20]CC)[S:15][C:11]=2[CH:10]=1)(=[O:8])=[O:7])C.C(C(CC)(C1C=CC=CC=1)C(P(=O)([O-])[O-])NS(C1C=CC2N=C(SCC3CCCCC3)SC=2C=1)(=O)=O)C>>[CH2:17]([S:16][C:14]1[S:15][C:11]2[CH:10]=[C:9]([S:6]([NH:5][CH:4]([P:25](=[O:26])([OH:27])[OH:28])[CH2:3][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)(=[O:7])=[O:8])[CH:24]=[CH:23][C:12]=2[N:13]=1)[CH2:18][CH2:19][CH3:20]

Participants

Reactant 2

HCID 131723856HCID 131723856, compound

HCID 131723858HCID 131723858, compound

Product 1

HCID 18551632HCID 18551632, compound

Procedure

The following titled compounds were prepared in a similar manner as above, except for employing (±)-diethyl-1-[(2-(n-hexylthio)benzthiazol-6-sulfonyl)amino]-2-phenylethylphosphonate (0.05 g, 0.087 mmol) and (±)-diethyl-1-[(2-(cyclohexylmethylthio)benzthiazol-6-sulfonyl)amino]-2-phenylethylphosphonate (0.05 g, 0.0858 mmol) prepared in Example 35 as starting materials.

Sources & evidence

ORD record: ord-d23ba612699d455ab68602016d143d5e
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06548667B2

Reaction notes

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