HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 1-(3-Amino-4-nitro-phenyl)-4-(2-chloro-phenyl)-1H-pyrrole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Chloro-2-nitroaniline | HCID 74218 | — |
| Reactant | 4-(2-Chlorophenyl)-1H-pyrrole-3-carbonitrile | HCID 12803535 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(3-Amino-4-nitro-phenyl)-4-(2-chloro-phenyl)-1H-pyrrole-3-carbonitrile | HCID 18548818 | — |
Reaction Steps
The title compound was prepared from 5-chloro-2nitroaniline, 4-(o-Chlorophenyl)-pyrrole-3-carbonitrile [CAS-No. 74738-15-1] and NaH in DMF at 150° C. for 3 h according to the general procedure E (method b). Obtained as a yellow-brown solid (218 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-31b2ed0aa7e9427cac1d297ed5e4c23c |
| Source note | uspto-grants-2003_04 |