HCID 69779703, compound → HCID 69779823, compound

HRID 1266746Notes

Reaction equation

HRID 1266746 reaction equation
[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][O:17][CH3:18])[C:11]([N:19]2[CH:23]=[CH:22][CH:21]=[CH:20]2)=[CH:10][C:9]=1[N+:24]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:27])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][O:17][CH3:18])[C:11]([N:19]2[CH:23]=[CH:22][CH:21]=[CH:20]2)=[CH:10][C:9]=1[NH2:24])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69779703HCID 69779703, compound

Product 1

HCID 69779823HCID 69779823, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The title compound was prepared from [5-(2-methoxy-ethoxy)-2-nitro-4-pyrrol-1-yl-phenyl]-carbamic acid tert.-butyl ester (Example A3) by hydrogenation with Raney-Nickel according to the general procedure J (method a). Obtained as an orange solid (196 mg).

Sources & evidence

ORD record
ord-d7699b2c201541cda72408e0b12b5f5b
Source dataset
uspto-grants-2003_04
Patent number
US06548495B2

Reaction notes

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