HCID 69780106, compound → HCID 69780012, compound

HRID 1266747Notes

Reaction equation

HRID 1266747 reaction equation
[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([N:16]2[CH:20]=[CH:19][CH:18]=[CH:17]2)=[CH:10][C:9]=1[N+:21]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:24])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([N:16]2[CH:20]=[CH:19][CH:18]=[CH:17]2)=[CH:10][C:9]=1[NH2:21])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69780106HCID 69780106, compound

Product 1

HCID 69780012HCID 69780012, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from (5-methoxy-2-nitro-4-pyrrol-1-yl-phenyl)-carbamic acid tert.-butyl ester (Example A4) (5.52 g, 16.6 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light pink solid (4.1 g).

Sources & evidence

ORD record
ord-aa47781015f74b98aa3ed58196a286da
Source dataset
uspto-grants-2003_04
Patent number
US06548495B2

Reaction notes

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