HCID 69780004, compound → HCID 69780025, compound

HRID 1266748Notes

Reaction equation

HRID 1266748 reaction equation
[C:1]([O:5][C:6](=[O:28])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([N:16]2[CH:20]=[CH:19][CH:18]=[C:17]2[C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:10][C:9]=1[N+:25]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:28])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH3:15])[C:11]([N:16]2[CH:20]=[CH:19][CH:18]=[C:17]2[C:21]([CH3:24])([CH3:23])[CH3:22])=[CH:10][C:9]=1[NH2:25])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69780004HCID 69780004, compound

Product 1

HCID 69780025HCID 69780025, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from [4-(2-tert.-butyl-pyrrol-1-yl)-5-methoxy-2-nitro-phenyl]-carbamic acid tert.-butyl ester (Example A5) (513 mg, 1.32 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light brown gum (110 mg).

Sources & evidence

ORD record
ord-0c41e532f7474444b2686cfcc8d31794
Source dataset
uspto-grants-2003_04
Patent number
US06548495B2

Reaction notes

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