HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → (2-Amino-4-cyano-5-thiomorpholin-4-yl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | (4-Cyano-2-nitro-5-thiomorpholin-4-yl-phenyl)-carbamic acid tert-butyl ester | HCID 69780718 | — |
| Product | (2-Amino-4-cyano-5-thiomorpholin-4-yl-phenyl)-carbamic acid tert-butyl ester | HCID 69780842 | — |
Reaction Steps
The title compound was prepared from (4-cyano-2-nitro-5-thiomorpholin-4-yl-phenyl)-carbamic acid tert-butyl ester (Example B4) (2.08 g, 5.71 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as an off-white solid (1.83 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-0b489df62c9a43ca9809a003eb8662d2 |
| Source note | uspto-grants-2003_04 |