HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Methyl-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Methyl-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69486745 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (2-Amino-5-methyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 67361461 | — |
Reaction Steps
The title compound was prepared from (5-methyl-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example B5) (3.40 g, 10.6 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as light gray solid (3.0 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-7a458700bbc847f2bac826aff41bf49f |
| Source note | uspto-grants-2003_04 |