HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (2-amino-5-morpholino-4-(trifluoromethyl)phenyl)carbamate → HCID 86586966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (2-amino-5-morpholino-4-(trifluoromethyl)phenyl)carbamate | HCID 12048026 | — |
| Reactant | 3-(2-Cyano-pyridin-4-yl)-3-oxo-propionic acid tert-butyl ester | HCID 69592816 | — |
| Product | HCID 86586966 | HCID 86586966 | — |
Reaction Steps
The title compound was prepared from (2-amino-5-morpholin-4-yl-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example J1) (181 mg, 0.5 mmol) and 3-(2-cyano-pyridin-4-yl)-3-oxo-propionic acid tert.-butyl ester (Example K3) (123 mg, 0.5 mmol) according to the general procedure M. Obtained as an off-white solid (137 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06548495B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-12da03e3c2b746d9a6650858c09174d5 |
| Source note | uspto-grants-2003_04 |