HCID 22224697, compound → HCID 18548906, compound

HRID 1266788Notes

Reaction equation

HRID 1266788 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([N:10]2[CH:14]=[CH:13][CH:12]=[CH:11]2)[CH:7]=[CH:6][C:5]=1[NH2:15])([O-:3])=[O:2].[I:16][C:17]1[CH:18]=[C:19]([C:23]2[O:28]C(C)(C)[O:26][C:25](=O)[CH:24]=2)[CH:20]=[CH:21][CH:22]=1>>[I:16][C:17]1[CH:18]=[C:19]([C:23](=[O:28])[CH2:24][C:25]([NH:15][C:5]2[CH:6]=[CH:7][C:8]([N:10]3[CH:14]=[CH:13][CH:12]=[CH:11]3)=[CH:9][C:4]=2[N+:1]([O-:3])=[O:2])=[O:26])[CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 22224697HCID 22224697, compoundHCID 22317392HCID 22317392, compound

Product 1

HCID 18548906HCID 18548906, compound

Procedure

The title compound was prepared from 2-nitro-4-pyrrol-1-yl-phenylamine (Example E1) (610 mg, 3 mmol) and 6-(3-iodo-phenyl)-2,2-dimethyl-[1,3]dioxin-4-one (Example L4) (1.49 g, 4.5 mmol) according to the general procedure M. Obtained as a brown solid (876 mg).

Sources & evidence

ORD record
ord-3d868747741449ae9fa631e638045839
Source dataset
uspto-grants-2003_04
Patent number
US06548495B2

Reaction notes

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