Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266793Generated: November 2, 2026

3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → 3-(3-Cyano-phenyl)-N-[5-(3-methoxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamide

https://huagongshe.com/reaction/1266793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrileHCID 11736337—
Reactant5-(3-Methoxymethyl-pyrrol-1-yl)-2-nitro-phenylamineHCID 18548853—
Product3-(3-Cyano-phenyl)-N-[5-(3-methoxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamideHCID 18548750—

Reaction Steps

The title compound was prepared from 5-(3-methoxymethyl-pyrrol-1-yl)-2-nitro-phenylamine (Example F7) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example L1) according to the general procedure M. Obtained as a yellow solid (102 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-3df8bb3e3c5744afbfe1da60cddb5e06
Source noteuspto-grants-2003_04