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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1266794Generated: November 3, 2026

3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → 3-(3-Cyano-phenyl)-N-[5-(2-methoxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamide

https://huagongshe.com/reaction/1266794

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrileHCID 11736337—
Reactant5-(2-Methoxymethyl-pyrrol-1-yl)-2-nitro-phenylamineHCID 18548817—
Product3-(3-Cyano-phenyl)-N-[5-(2-methoxymethyl-pyrrol-1-yl)-2-nitro-phenyl]-3-oxo-propionamideHCID 18548897—

Reaction Steps

The title compound was prepared from 5-(2-methoxymethyl-pyrrol-1-yl)-2-nitro-phenylamine (Example F8) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example L1) according to the general procedure M. Obtained as a light brown solid (620 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06548495B2
Source datasetuspto-grants-2003_04
ORD IDord-ed5723314a0d4f7691a39d21ec00ded6
Source noteuspto-grants-2003_04