6-(3-Imidazol-1-yl-phenyl)-2,2-dimethyl-[1,3]dioxin-4-one → {2-[3-(3-Imidazol-1-yl-phenyl)-3-oxo-propionylamino]-4-pyrrol-1-yl-phenyl}-carbamic acid tert.-butyl ester

Participants

Reaction Steps

The title compound was prepared from (2-amino-4-pyrrol-1-yl-phenyl)-carbamic acid tert.-butyl ester (Example J2) (1.37 g, 5.0 mmol) and 6-(3-imidazol-1-yl-phenyl)-2,2-dimethyl-[1,3]dioxin-4-one (Example L3) (1.28 g, 4.75 mmol) according to the general procedure M. Obtained as a light brown foam (1.78 g).

Provenance & Evidence