HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester → HCID 86586986, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert-butyl ester | HCID 12048028 | — |
| Edukt | (2-Amino-5-fluoro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489617 | — |
| Produkt | HCID 86586986 | HCID 86586986 | — |
Reaktionsschritte
The title compound was prepared from (2-amino-5-fluoro-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example J10) (294 mg. 1.0 mmol) and (RS)-3-oxo-3-{3-[5-(tetrahydro-pyran-2-yloxymethyl)-[1,2,3]triazol-1-yl]-phenyl}-propionic acid tert.-butyl ester (Example K5) (442 mg, 1.1 mmol) according to the general procedure M. Obtained as an orange solid (509 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06548495B2 |
| Quelldatensatz | uspto-grants-2003_04 |
| ORD ID | ord-95c3107da92f4f41bf8ecd66d6c0f537 |
| Quellennotiz | uspto-grants-2003_04 |