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HRID1266832

反应详情

EQUATION

反应方程式

HRID 1266832 的结构方程式

REACTANTS

反应物

1
结构：N#Cc1cccc(C(=O)CC(=O)Nc2cc(-n3cc(C#N)c(-c4ccccc4Cl)c3)ccc2[N+](=O)[O-])c1
HCID18548747

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1cccc(C2=Nc3ccc(-n4cc(C#N)c(-c5ccccc5Cl)c4)cc3NC(=O)C2)c1
HCID18548852

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O.[Fe]
催化剂HCID45051903

未命名化合物

结构：C1CCOC1.O
溶剂HCID21881883

Oxolane--water (1/1)

C4H10O2

PROCEDURE

实验过程

The title compound was prepared from N-{5-[3-(2-chloro-phenyl)-4-cyano-pyrrol-1-yl]-2-nitro-phenyl}-3-(3-cyano-phenyl)-3-oxo-propionamide (Example M6) by reductive cyclization with Fe/HOAc in THF/H2O at 80° C. according to the general procedure J (method d). Obtained as a brown solid (164 mg).