2-Chlorobenzyl chloride → HCID 10224587, compound

HRID 1267025Notes

Reaction equation

HRID 1267025 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:31])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH:19]([OH:30])[CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][C:25](OC)=[CH:24][CH:23]=2)[CH2:14][CH2:13]1.[Cl:32]C1C=CC=CC=1CCl.COC1C=CC(CCl)=CC=1>>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[O:31])[CH2:11][N:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH:19]([OH:30])[CH2:20][CH2:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[Cl:32])[CH2:14][CH2:13]1

Participants

4

Reactant 3

HCID 119062-Chlorobenzyl chlorideHCID 699934-Methyloxybenzyl chlorideHCID 12052937N-(2,6-dimethylphenyl)-2-{4-[4-(4-methoxyphenyl)-2-hydroxybutyl]piperazinyl}acetamide

Product 1

HCID 10224587HCID 10224587, compound

Procedure

Compound 18 was prepared in a manner similar to that of compound 16 substituting 2-chlorobenzyl chloride for 4-methoxybenzyl chloride. (M+1)=430.2

Sources & evidence

ORD record
ord-a4b173c4198f45d8b0fdca2278c59aab
Source dataset
uspto-grants-2003_04
Patent number
US06552023B2

Reaction notes

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