Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1267028Generated: October 26, 2026

4-Methyloxybenzyl chloride → n-(2,6-Dimethylphenyl)-2-[4-(2-hydroxy-5-phenylpentyl)piperazinyl]acetamide

https://huagongshe.com/reaction/1267028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyloxybenzyl chlorideHCID 69993—
ReactantN-(2,6-dimethylphenyl)-2-{4-[4-(4-methoxyphenyl)-2-hydroxybutyl]piperazinyl}acetamideHCID 12052937—
Productn-(2,6-Dimethylphenyl)-2-[4-(2-hydroxy-5-phenylpentyl)piperazinyl]acetamideHCID 10158442—

Reaction Steps

Compound 25 was prepared in a manner similar to that of 16, substituting phenethyl chloride for 4-methoxybenzyl chloride in part A. (M+1)=410.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06552023B2
Source datasetuspto-grants-2003_04
ORD IDord-b718d0ac97c94f00a005ad817129ad0b
Source noteuspto-grants-2003_04