HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-Fluorophenyl 2-propenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Fluorophenyl 2-propenoate | HCID 18546000 | — |
Reaction Steps
For example: Acryloyl chloride and 4-fluorophenol react in dichloromethane in the presence of triethylamine to give 4-fluorophenyl acrylate 10 (R=4-fluorophenyl). Compound 10 is then added to a solution of 9 in ethanol and diethylamine to give 11 (R=4-fluorophenyl) after usual workup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552046B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-aa96dff16a2e40b292b75db62f001a42 |
| Source note | uspto-grants-2003_04 |