HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 67206808, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | Norcisapride | HCID 3019427 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 67206808 | HCID 67206808 | 118.2% |
Reaction Steps
A mixture containing 313 mg norcisapride and 276 mg potassium carbonate in 10 ml DMF was treated with 153 mg of bromo-acetic acid methyl ester. The reaction was stirred at ambient temperature for 8 hr. Extractive workup with waterdichloromethane followed by flash chromatography afforded 455 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552046B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-c9fdb13b3c1b4f5dbb3066c85bd006d0 |
| Source note | uspto-grants-2003_04 |