HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutyl iodide → 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutyl iodide | HCID 10556 | — |
| Reactant | RO-05-2921 | HCID 76175 | — |
| Product | 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one | HCID 22312025 | — |
Reaction Steps
1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (prepared according to the procedure of M. G. Bock et al., J. Org. Chem. 1987, 52, 3232-3239, incorporated herein by reference) was alkylated with isobutyl iodide using General Procedure 8-G to afford 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06552013B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-33943cb705484be19e15cc2a082ce8a4 |
| Source note | uspto-grants-2003_04 |