反应详情

Activated manganese dioxide (2.8 g) was added to a solution of (E)-3-[4-[2-[5-methyl-2-(3-methylphenyl)-4-oxazolyl]ethoxy]phenyl]-2-propen-1-ol (1.4 g) in dichloromethane (50 ml). The mixture was stirred for 2 hours at room temperature, which was subjected to filtration through celite. The filtrate was concentrated to give (E)-4-[2-[5-methyl-2-(3-methylphenyl)-4-oxazolyl]ethoxy]cinnamaldehyde (1.27 g, 91%). Recrystallization from dichloromethane-isopropyl ether gave colorless needles, m.p.110-111° C.

1. filtrationwhich was subjected to filtration through celite
2. concentrationThe filtrate was concentrated