2,5-Dimethylaniline → 2-[(2,5-Dimethylphenyl)amino]phenylacetic acid

HRID 1267342Notes

Reaction equation

HRID 1267342 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10].[CH3:12][C:13]1[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][C:14]=1[NH2:15]>>[CH3:12][C:13]1[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][C:14]=1[NH:15][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 72592,5-DimethylanilineHCID 877542-Bromophenylacetic acid

Product 1

HCID 185463702-[(2,5-Dimethylphenyl)amino]phenylacetic acid

Procedure

In the manner described in example 3, 2-bromophenylacetic acid is condensed with 2,5-dimethylaniline to yield 2-[(2,5-dimethylphenyl)amino]phenylacetic acid.

Sources & evidence

ORD record
ord-9691ff8e6554498390b26eb5ec25d3e5
Source dataset
uspto-grants-2003_04
Patent number
US06552077B2

Reaction notes

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